Risk L5, Medicine I 38 The medical breakthrough of the original biologic medication for Crohn's disease was first reported in 1998. There are now 6 in use for IBD, known best by their commercial names, Cimzia, Humira, Remicade and recently Simponi (listed alphabetically) and Entyvio and Stelara (which are different in the way they work). … Continue reading MEDICATION RISKS AND BENEFITS: BIOLOGICS–THE ANTI-TNFs